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Tadalista 10 mg is a medicine containing tadalafil, an active ingredient used to treat erectile dysfunction (ED) in adult men. Erectile dysfunction is the difficulty of achieving or maintaining an erection sufficient for sexual activity. Tadalafil belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. Tadalafil blocks the PDE5 enzyme, helping relax blood vessels and improve blood flow to the penis. Its effects may last up to 36 hours, although individual responses vary. This does not mean an erection should last continuously.